Achievement Award

Pier Giorgio Righetti

Prof. Righetti earned his Ph. D. in Organic Chemistry from the University of Pavia in 1965. He then spent 3 years as a Post. Doc. at MIT and 1 year at Harvard (Cambridge, Mass, USA). He is full professor of Proteomics at the Milan’s Polytechnic.

He is in the Editorial Board of Electrophoresis, J. Proteomics, BioTechniques, Proteomics, Proteomics Clinical Applications. He has co-authored the book Boschetti, E. Righetti, P.G. Low-Abundance Proteome Discovery; State of the Art and Protocols, Elsevier, Amsterdam, 2013, pp. 1-341. More information on the book is below.

He has developed isoelectric focusing in immobilized pH gradients, multicompartment electrolyzers with isoelectric membranes, membrane-trapped enzyme reactors, temperature-programmed capillary electrophoresis and combinatorial peptide ligand libraries for detection of the low-abundance proteome.

On 560 articles reviewed by the ISI Web of Knowledge (Thomson Reuters), Righetti scores 18.890 citations, with an average of 33 citations/article and with a H-index of 60. Only in the last eight years (2005-2012) he has received citations ranging from 1000 to 1200 per year. He has won the CaSSS (California Separation Science Society) award (October 2006), at that time in its 12th edition, and the Csaba Horvath Medal award, presented on April 15, 2008 by the Connecticut Separation Science Council (Yale University). In 2011, he has been nominated honorary member of the Spanish proteomics society and in 2012 he has won the prestigious Beckman award and medal granted in February at the Geneva MSB meeting.

Prof. Righetti will be presenting his talk, "The Monkey King: a personal view of the long journey towards a proteomic Nirvana".

Low-Abundance Proteome Discovery; State of the Art and Protocols

Egisto Boschetti Scientific Consultant, Paris, France and Pier Giorgio Righetti Miles Gloriosus Academy, Milano, Italy

This book addresses the biggest challenge in the field of protein biomarkers – detecting low‐abundance proteomes – and offers novel methods and protocols for their detection, identification, and quantification.

Key Features

  • Covers methodologies for enhancing the visibility of low abundance proteins which, until now, has been the biggest challenge in biomarker progress
  • Includes detailed protocols that address real life needs in laboratory practice
  • Addresses all applications, including human disease, food and beverage safety, and the discovery of new proteins/peptides of importance in nutraceutics
  • Compiles the research and analytic protocols of the two scientists who are credited with the discovery of these landmark methodologies, also known as combinatorial peptide ligand libraries, for the identification of low abundance proteins

Description

Low‐Abundance Proteome Discovery addresses the most critical challenge in biomarker discovery and progress: the identification of low‐abundance proteins. The book describes an original strategy developed by the authors that permits the detection of protein species typically found in very low abundance and that may yield valuable clues to future discoveries. Known as combinatorial peptide ligand libraries, these new methodologies are one of the hottest topics related to the study of proteomics and have applications in medical diagnostics, food quality, and plant analysis. The book is written for university and industry scientists starting proteomic studies of complex matrices (e.g., biological fluids, biopsies, recalcitrant plant tissues, foodstuff, and beverage analysis), researchers doing wet chemistry, and graduate‐level students in the areas of analytical and biochemistry, biology, and genetics.

RELATED TITLES

  • Proteomics & Peptidomics, Marko Varga, 9780444518101, $390, 662 pp, 12/2005, Elsevier.
  • The Proteome Revisited, (Vol. 63 J Chrom Library), Stoyanov, 9780444505262, $250, 410 pp, 10/2001, Elsevier.
  • Protein Mass Spectrometry, Whitelegge, 9780444530554, $275, 552 pp, 10/2008, Elsevier.
  • Protein Biochemistry and Proteomics, Rehm, 9780120885459, $57.95, 256 pp, 02/2006, Academic Press.
  • ISBN: 978‐0‐12‐401734‐4
  • PUB DATE: May 2013
  • LIST PRICE: $119.95
  • DISCOUNT: Agency
  • FORMAT: Paperback
  • PAGES: 342
  • TRIM: 8.5w x 10.875h
  • AUDIENCE
    Analytical chemists, biochemists, clinical chemists, biologists, including graduate‐level students in these disciplines; genetic and biomedical researchers

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